It can be confmaking use of to pick in between Wellbutrin vs Lexapro. We break down the differences and similarities of Wellbutin and also Lexapro you need to recognize.

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When we battle with our mental wellness or a depressive disorder, it can be difficult to select the ideal treatment arrangement. If you’re considering prescription drugs, two popular antidepressants are Wellbutrin and also Lexapro.

When we take a cshed look at Wellbutrin vs Lexapro, which comes out on top? The answer varies for each individual. But if you’re trying to decide which is finest for you, it helps to look at each medication and view which may better suit your needs, wellness, and lifestyle. Tbelow are some considerable distinctions in between Lexapro and also Wellbutrin, with each having its benefits and also disadvantages.

In this Minded Guide, we’ll take a closer look at both drugs and also what you must understand if you’re taking them for the first time or considering replacing Lexapro through Wellbutrin (or vice versa). This information have the right to provide you the confidence to make a sound decision.

Read on to learn even more around the 2 medications, including:

An arrival to Wellbutrin and Lexapro A breakdvery own in between the specifics of Wellbutrin vs LexaproLexapro vs Wellbutrin: exactly how to decide which medication is better for youUsing Lexapro and also Wellbutrin together


Wellbutrin and Lexapro

Wellbutrin and Lexapro are both offered to treat mild, modeprice, and major depression. Both medicines influence our mood and psychological health yet are not the same course or form of drug, as each targets various brain molecules and receptors. Lexapro is a selective serotonin reuptake inhibitor (SSRI), while Wellbutrin is a norepinephrine/dopamine reuptake inhibitor (NDRI). These two reuptake inhibitors occupational in different ways. NDRIs block the actions of the neurotransmitters norepinephrine and dopamine cell receptor transporters, while the SSRIs restrict brain cells from soaking up serotonin—thus, accumulating more serotonin in the area in between brain cells, for its action to be stronger and longer. Aacquire, the best option relies on the individual.

Unlike tricyclic antidepressants, including amitriptyline or doxepin, medications prefer Wellbutrin and also Lexapro have actually low anticholinergic results. That means they are less likely to lead to side results favor memory difficulties and also confusion. Medications via high anticholinergic effects have actually been attached to greater dementia hazard. Drugs with high anticholinergic results likewise create more constipation, obstacle urinating, blurry vision, and dry mouth.

In summary, Wellbutrin and also Lexapro are both antidepressant drugs, though they differ in the way they work-related. They both have actually other provides that can make them a far better fit for you.

Let’s look at the difference in response for each medication. Remember, when you look at Wellbutrin vs Lexapro, store in mind what is a lot of crucial in your health and wellness care.

A closer look: Wellbutrin

Wellbutrin is the brand name of the generic drug bupropion. Zyban is another brand name the drug bupropion goes by, supplied particularly to aid people stop cigarette smoking (in reduced doses than for treating depression).

Wellbutrin was apconfirmed in 1985 and is used a lot of generally to treat depression, major depressive disorder (MDD), and also seasonal affective disorder (SAD). It have the right to also assist through smoking cessation.


Many civilization who use Wellbutrin report feeling innovation within 1-2 weeks after starting on an initial dosage; advancement from even more serious states of depression deserve to take 6-8 weeks. The dosage a perboy is on may also impact its oncollection of activity. 

Doctors could prescribe Wellbutrin for “off-label” provides, interpretation different from its apshowed usage from the Food and also Drug Administration (FDA). “Off-label” prescribing is very prevalent and within the requirements of top quality clinical treatment. Wellbutrin can be taken for conditions such as social tension disorder and bipolar disorder. It’s also provided as a “second-line medication” for ADHD (attention deficit hyperactivity disorder), meaning it is unified with psychostimulants like Adderall. While the Wellbutrin dosage might vary, it’s commonly prescribed at 150 mg per day.

Wellbutrin comes in three different preparations:

Wellbutrin or bupropion SR for continual releaseWellbutrin XL for extfinished release Wellbutrin IR for instant release

The preparation of Wellbutrin you take will identify exactly how lengthy it stays in your body and brain. Its duration of activity is a element in just how long it will certainly impact you. Discuss your taracquire dose via your medical professional or one of Minded’s professionals.

Side effects

The widespread side results of Wellbutrin include headache, weight loss, dry mouth, insomnia, nausea, and constipation. You could additionally suffer an irregular or quick heart rate, moodiness, or restlessness.

Less prevalent but even more significant side impacts might incorporate seizures, cardiovascular (heart and also blood vessel) problems, or worsening depression. Those taking Wellbutrin for cigarette smoking cessation might notification a adjust in their mood, for better or worse.

Talk to your doctor around any worsening of your depressive symptoms or the oncollection of panic assaults or suicidal thoughts.

Wellbutrin’s side impacts usually decrease within the initially few weeks of taking the drug. The severity of side effects also might depfinish on certain existing clinical conditions you may have actually, including high blood push, irregularities in your heartbeat, a mind tumor, liver condition, substance use disorder, or eating disorders.

Be certain to talk via your physician prior to taking Wellbutrin if you have actually a background of any of these problems. You can likewise comment on any comes to via one of the professionals at Minded.


The FDA has actually put Wellbutrin in category B for pregnancy, meaning that pet research studies have actually not shown danger to the fetus. Tbelow are no sufficient studies on its result on humans, so we cannot preeminence out the hazard of taking Wellbutrin if you are pregnant. Due to the fact that depression deserve to negatively affect your pregnancy or the care of your infant, it is essential for you and your doctor to consider the dangers and benefits of making use of it.

Wellbutrin is lugged by breast milk to a nursing boy. If you continue to use Wellbutrin while breastfeeding, be certain to discuss via your pediatrician and pay careful attention to any transforms you observe in your nursing infant’s behavior.

It’s recommended that you not drink alcohol once taking Wellbutrin; it have the right to worsen its side effects. If you are susceptible to seizures, drinking alcohol via Wellbutrin ca rise the danger of having actually them.

Consult via your physician or a Minded clinician around any kind of various other drugs you are taking to take into consideration if Wellbutrin will cause any adverse problematic drug interactions. If you are taking Wellbutrin to speak cigarette smoking, consult with your doctor if you’re taking anything else in your initiative to quit tobacco. 

Most human being report mild to no withdrawal symptoms from Wellbutrin. Though if you’re making use of it to quit smoking, you might alert your nicotine cravings return.

A closer look: Lexapro

Lexapro, the brand also name of the generic drug escitalopram, was apverified in 2002. It is an SSRI. It is greatly provided for depression and major depression, and also anxiety and generalised tension disorder (GAD).


People who take Lexapro report enhancements in energy, sleep high quality, mood, and also appetite, often within 1-2 weeks. With more severe problems, enhancements might take 6-8 weeks. The typical dosage for Lexapro is 10-20 mg per day, depending on your age, weight, any kind of medical problems you may have actually, and also various other medicines (and also supplements) you might be taking. Off-label uses of Lexapro include therapy for obsessive-compulsive disorders (OCD) and also panic disorders.

Side effects

Lexapro’s widespread side results incorporate headache, nausea, sweating, restlessness, exhaustion, insomnia, and also transforms in body weight. Some individuals endure sex-related side results, consisting of sex-related arousal disorder, sex-related desire disorder, and also orgasm dysattribute. Many type of civilization experience diminished sex drive or reduced libiperform as a side impact. 

Weight get is not common on Lexapro. But if diminished appetite was among your factors for taking Lexapro, you may experience weight gain from an improvement in your appetite. Lexapro have the right to worsen depression symptoms, so instantly speak with your physician or therapist if you suffer suicidal thoughts.

Severe side effects have the right to occur through Lexapro, favor high blood pressure, also well-known as hyperstress. Lexapro likewise may cause serotonin syndrome, identified by symptoms that encompass agitation, fever, hallucinations, diarrhea, heartbeat irregularities, and also restlessness. If that happens, contact your physician automatically.


Lexapro is in category C for pregnancy, which indicates tright here have actually been animal studies that display a perhaps harmful impact on the fetus. Not sufficient research studies have actually been done to confirm the danger on huguy fetprovides. Lexapro does bring the danger of premature birth once taken in the second and also third trimesters of pregnancy.

You, your physician, or a Minded expert will must balance these threats with the potential benefits of Lexapro, consisting of your health during pregnancy. Lexapro is lugged in breastern milk to the nursing son, so carefully monitor your baby’s health for any unusual or abnormal effects.

You must avoid drinking alcohol while taking Lexapro. Some civilization find that an overly restrictive suggestion; for those that carry out, talk to your physician or a Minded experienced for information around utilizing alcohol in little amounts. 

If you’re taking Lexapro with other drugs, inspect through your medical professional to watch if there will be any problems through combining Lexapro through the other medicines you are taking. Some significant drugs to pay attention to are antipsychotics, SSRIs, blood thinners, or lithium. 

Please be conscious that all of a sudden stopping your usage of Lexapro deserve to produce withdrawal symptoms, so it is ideal to slowly mitigate its dose, as advised by your physician. Withdrawal symptoms may include headache, agitation, mood swings, and difficulty concentrating.

Contact your doctor if you experience significant symptoms — choose wanting to take your life.

Wellbutrin vs Lexapro: Which is better?

There is no clear-cut answer in picking between Lexapro and also Wellbutrin. That is bereason each perchild is different, via possibly different responses and also sensitivities to a medication.

Both drugs have actually been efficient in depressed patients. Your choice will be more indeveloped by the indevelopment here, as well as speaking with your medical professional or a Minded expert around any difference in favor of one or the various other, as well as if SSRIs or NDRIs are most likely to be a far better alternative for you.

Your medication goals, in enhancement to dealing with your depression, prefer reducing anxiety or curbing your cigarette smoking, deserve to aid you select in between Lexapro vs Wellbutrin. Your doctor can likewise imply making use of one or the various other to help through other, off-label conditions.

Side effects: Wellbutrin vs Lexapro

Wellbutrin have the right to have actually fewer side effects, especially not producing reductions in libiexecute and sexual dysfunction. In one clinical trial, Wellbutrin had actually fewer sex-related side results than various other antidepressants, including Lexapro.

But if you have clinical problems in enhancement to depression, or a background of specific illnesses in your family members, Wellbutrin may not be the appropriate option for you; this is essential to discuss through your physician in order to minimize any kind of serious side effects or reactions.

Warnings: Wellbutrin vs Lexapro

In regards to pregnancy, neither medication is thought about totally safe since neither have actually had enough humale research studies to encertain their security. But the FDA does categorize Wellbutrin in a much more secure course than Lexapro, so it is potentially safer for usage in those who are pregnant. Both antidepressants deserve to assist via postpartum depression, quite common, especially in those via a background of depression. Recall, as noted over, that both pass in the breast milk to the nursing kid. Be sure to talk to your physician around the risks of using Lexapro vs Wellbutrin if breastfeeding your infant.

Verdict: Wellbutrin vs Lexapro

Is Lexapro much better than Wellbutrin, or does Wellbutrin job-related much better than Lexapro? We know that one of the a lot of substantial distinctions is Lexapro’s potential to reason sex-related dysattribute side effects. And we understand that Wellbutrin carries more threat if you are at risk to seizures.

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More answers lie in understanding each person’s requirements, age, and weight, the use of various other medicines, the person’s clinical problems, and clinical background. Taking the time to consider these matters with your doctor can make a significant distinction in your reaction to either medication. 

Wellbutrin and Lexapro together

Clinical researches have actually presented that taking Wellbutrin and also Lexapro together deserve to create beneficial results. Combining Wellbutrin and Lexapro together deserve to improve symptoms in depressed patients. Talk to your medical professional or a Minded experienced to uncover out if the combicountry could work for you.

Final thoughts: Wellbutrin vs Lexapro: Which medication is much better for you?

Lexapro and Wellbutrin both assist in the active therapy of stress and also depression disorders.

They likewise have various other supplies, like Wellbutrin aiding smoking cigarettes cessation and also Lexapro helping anxiety.

Both medications have actually staminas and weaknesses. When deciding if Wellbutrin (bupropion) vs Lexapro (escitalopram) is better, seek the clinical advice of your health and wellness treatment provider to determine which one might ideal serve your needs.

If you’re in search of a new solution to getting your medication, try Minded’s medication renewal arrangement. Medications delivered straight to your door. Contact us for more information.